We've done almost all settings in WordPress. For general website operation, you just need to handle "Pages" and "Posts". And it's very simple and user-friendly actually.
"Pages":
(your web pages creation and organization)http://codex.wordpress.org/Pages#Creating_Pages
"Posts":
(not a must, as it's function is similar to "Pages". only suggested for categories with lots of level 2 sub-pages that you don't want to show all of them on level 1 of every web page.)http://codex.wordpress.org/Writing_Posts
